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Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

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Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
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Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

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Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
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Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

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Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
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Acute Coronary Syndrome IV: Interprofessional Care01:28

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IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
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Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors01:20

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors

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Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
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The Current Landscape of Anticoagulation Stewardship Implementation in the United States and Around the World: An International Survey.

Journal of the American College of Clinical Pharmacy : JACCP·2026
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2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

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Impact of Hospital-based Multidisciplinary Anticoagulation Stewardship Programs.

Mateo Porres-Aguilar1, Jack Ansell2, Debabrata Mukherjee3

  • 1Department of Internal Medicine, Divisions of Hospital and Adult Thrombosis Medicine, Texas Tech University Health Sciences Center and Paul L. Foster School of Medicine, El Paso, Texas, USA; Sociedad Mexicana de Trombosis y Hemostasia, Ciudad de México, México.

Archives of Medical Research
|December 8, 2022
PubMed
Summary
This summary is machine-generated.

Implementing a multidisciplinary anticoagulation stewardship program (MASP) is crucial for high-risk antithrombotic therapies. MASPs improve patient outcomes, reduce adverse events, and optimize healthcare resource use.

Keywords:
Adverse drug eventsAnticoagulantsAntithrombotic therapiesMultidisciplinary anticoagulation stewardship programsVenous thromboembolism

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Area of Science:

  • Pharmacology
  • Clinical Medicine
  • Healthcare Management

Background:

  • Antithrombotic therapies, particularly anticoagulants, are essential but carry significant risks of adverse events.
  • Managing these medications requires careful oversight to ensure patient safety and therapeutic efficacy.

Purpose of the Study:

  • To review the critical need for antithrombosis stewardship.
  • To discuss the benefits of establishing a formal multidisciplinary anticoagulation stewardship program (MASP).

Main Methods:

  • Literature review and discussion of existing evidence on anticoagulation management.
  • Analysis of the components and objectives of a well-functioning MASP.

Main Results:

  • MASPs aim to improve patient-centered outcomes and minimize anticoagulation-related adverse events.
  • These programs help reduce hospital length of stay (LOS) and associated costs.
  • MASPs support clinicians, ensure resource optimization, and aid in meeting accreditation standards.

Conclusions:

  • Formalized MASPs are pivotal for optimizing the use of antithrombotic therapies.
  • Implementing MASPs positively impacts patient morbidity and mortality outcomes.