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Musculoskeletal complications in long COVID-19: A systematic review

Raktim Swarnakar1, Shoibam Jenifa1, Sanjay Wadhwa2

  • 1Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India.

World Journal of Virology
|December 9, 2022
PubMed

Insights

Long COVID frequently causes musculoskeletal issues like fatigue, myalgia, and arthralgia. Research gaps exist in understanding and treating these long COVID complications, particularly rehabilitation strategies.

Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Rehabilitation Medicine

Background:

  • Coronavirus disease 2019 (COVID-19) has led to various long-term health issues.
  • Musculoskeletal symptoms are common in acute COVID-19 but underreported in long COVID.
  • Persistent fatigue, myalgia, and arthralgia are frequently reported by COVID-19 survivors.

Purpose of the Study:

  • To systematically review and identify musculoskeletal complications associated with long COVID.
  • To assess the existing literature on rehabilitation interventions for long COVID musculoskeletal issues.

Main Methods:

  • A systematic review of existing systematic reviews and meta-analyses was conducted.
  • Screened 63 articles, including 24 relevant studies.
  • Identified specific focus areas within the included literature, noting limitations.

Main Results:

  • Fatigue emerged as the most prevalent musculoskeletal complication in long COVID.
  • Myalgia and arthralgia were also commonly reported.
  • A significant lack of studies specifically addressing rehabilitation interventions for long COVID musculoskeletal issues was found.

Conclusions:

  • Fatigue, myalgia, and arthralgia are significant musculoskeletal complications of long COVID.
  • There is a critical need for research into standardized rehabilitation interventions for these complications.
  • Further studies are essential to address functional impairment and guide effective treatment strategies.
Abstract

Keywords:
COVID-19Long COVID-19Musculoskeletal complicationsPost-COVID-19 syndromeRehabilitationSARS-CoV-2

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