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Evans' syndrome following vaccination with ChAdOx1 nCoV-19 in a patient with new-onset localized scleroderma
Thilo Gambichler1, Pia Nordmann1, Christina Scheel1
1Skin Cancer Center, Department of Dermatology, Ruhr-University Bochum, Germany.
Abstract:
Growing evidence suggests that COVID-19 vaccines can induce hematological conditions. Here, we report a case of Evans' syndrome, a combination of immune thrombocytopenic purpura and autoimmune hemolytic anemia following administration of the ChAdOx1 nCoV-19 vaccine. The present case further supports the notion that COVID-19 vaccines can trigger in rare cases severe persistent autoimmune-mediated hematological conditions which may predominantly occur in patients with underlying autoimmune conditions.
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