A flexible 16-channel custom coil array for accelerated imaging of upper and infraglottic airway at 3 T

To develop a custom coil and evaluate its utility for accelerated upper and infraglottic airway MRI at 3 T.

A 16-channel flexible and anatomy-conforming coil was developed to provide localized sensitivity over upper and infraglottic airway regions of interest. Parallel-imaging capabilities were compared against existing head and head-neck coils. SENSE geometry factor losses were quantified for retrospectively accelerating 3D MRI. Blinded image-quality ratings from two experts were performed. Spiral GRAPPA reconstructions were evaluated for a speaking task at a time resolution of 40 ms. Contrast-to-noise ratios between air and tissue at key landmarks along the vocal tract were compared. SENSE imaging with the custom coil in the lateral recumbent posture was evaluated. Multislice imaging was performed to image swallowing at 17 ms/frame via constrained reconstruction.

The custom coil showed improved SENSE imaging up to 3-fold acceleration when accelerated along either the anterior-posterior or the superior-inferior direction and a net 4-fold acceleration when accelerated along both directions. Spiral GRAPPA reconstructions with the custom coil showed higher contrast-to-noise ratio when compared with existing coils. In the lateral posture, robust SENSE imaging was achieved at up to 2-fold and 3-fold acceleration levels in the superior-inferior and anterior-posterior directions, respectively. Key events of swallowing in the multislice dynamic images were identified by an otolaryngologist.

The coil provided improved parallel imaging of upper and infraglottic airway in both supine and lateral recumbent postures. It enabled efficient accelerated dynamic imaging of speaking and swallowing.