Related Experiment Video
Updated: Aug 18, 2025

06:15
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
1.3K
The corneo-scleral junction assessed with optical coherence tomography
Maria Muzyka-Woźniak1, Adam Oleszko1, Łukasz Stróżecki2
1Ophthalmology Clinical Centre SPEKTRUM, Wrocław, Poland.
Plos One
|December 9, 2022
Summary
The temporal corneo-scleral junction (CSJ) is wider and more regular than the nasal CSJ, with patterns independent of age or refractive error. This AS-OCT analysis may improve horizontal visible iris diameter measurements.
Area of Science:
- Ophthalmology
- Biomedical Imaging
- Anatomy
Background:
- The corneo-scleral junction (CSJ) is a critical anatomical landmark.
- Understanding its structure is essential for various ophthalmic procedures.
- Anterior Segment Optical Coherence Tomography (AS-OCT) offers high-resolution imaging of ocular structures.
Purpose of the Study:
- To evaluate the corneo-scleral junction (CSJ) using anterior segment optical coherence tomography (AS-OCT).
- To describe the interfusion pattern of the cornea and sclera based on tissue reflectivity.
- To investigate potential correlations between CSJ characteristics and ocular parameters.
Main Methods:
- Prospective observational study of 101 eyes undergoing vision correction assessment.
- AS-OCT horizontal scans to measure temporal and nasal CSJ width and reflectivity.
- Correlation and regression analyses performed with age, spherical equivalent, anterior chamber angle, and horizontal visible iris diameter (HVID).
Main Results:
- Temporal CSJ was significantly wider (median 1.62 mm) than nasal CSJ (median 1.18 mm).
- Temporal CSJ reflectivity was predominantly V- or U-shaped, while nasal CSJ was irregular in 47% of cases.
- Temporal CSJ width correlated negatively with anterior chamber angle and positively with HVID; nasal CSJ showed no significant correlations.
Conclusions:
- The temporal CSJ is wider and more regularly reflective than the nasal CSJ.
- CSJ width is independent of age and refractive error.
- AS-OCT analysis of CSJ morphology may enhance the accuracy of HVID measurements.
Related Concept Videos
Angle Closure Glaucoma: Treatment
613
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
613
Glaucoma: Overview
680
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
680
Open Angle Glaucoma: Treatment
520
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
520

