Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Viral Mutations00:36

Viral Mutations

32.7K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
32.7K
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

170
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
170
Viral Recombination00:57

Viral Recombination

23.7K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genetic characteristics of the isolate of human adenovirus type 55 (<i>Adenoviridae: Mastadenovirus</i>) isolated in Moscow in 2022.

Voprosy virusologii·2025
Same author

[Epidemic season 2023-2024: the palette of ARVI pathogens in some territories of the Russian Federation and WHO regions].

Voprosy virusologii·2025
Same author

[Impact of COVID-19 pandemic on the etiology and severity of respiratory viral infections in children].

Voprosy virusologii·2025
Same author

Analysis of the association of influenza clinical course with single nucleotide polymorphisms in genes affecting the interferon-λ3 production.

Voprosy virusologii·2025
Same author

[Association of polymorphic variants of hemostatic system genes with the course of COVID-19].

Voprosy virusologii·2023
Same author

DRIFT OF INFLUENA A(H3N2) VIRUS: BIOLOGICAL, ANTIGENIC AND GENETIC PROPERTIES IN EPIDEMIC SEASON 2016-2017 IN RUSSIA AND COUNTRIES OF THE NOTHERN HEMYSPHERE.

Voprosy virusologii·2022

Related Experiment Video

Updated: Aug 18, 2025

Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses
08:10

Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses

Published on: January 15, 2020

8.4K

FEATURES OF EPIDEMIC PROCESS OF INFLUENZA A(H1N1)PDM09 AND A(H3N2) IN RUSSIA FROM 2009 TO 2017.

L S Karpova1, K M Volik1, K A Stolyarov1

  • 1Federal State Research Institute of Influenza.

Voprosy Virusologii
|December 10, 2022
PubMed
Summary

Influenza A(H1N1)pdm09 epidemics decreased in intensity and mortality, except for those over 65. Influenza A(H3N2) showed increasing severity, particularly in older adults, highlighting pandemic influenza

Keywords:
influenza epidemic A(H3N2) and A(H1N1)pdm09morbiditymortality

More Related Videos

High-throughput Detection Method for Influenza Virus
10:05

High-throughput Detection Method for Influenza Virus

Published on: February 4, 2012

26.3K
Nasal Wipes for Influenza A Virus Detection and Isolation from Swine
05:59

Nasal Wipes for Influenza A Virus Detection and Isolation from Swine

Published on: December 4, 2015

9.5K

Related Experiment Videos

Last Updated: Aug 18, 2025

Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses
08:10

Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses

Published on: January 15, 2020

8.4K
High-throughput Detection Method for Influenza Virus
10:05

High-throughput Detection Method for Influenza Virus

Published on: February 4, 2012

26.3K
Nasal Wipes for Influenza A Virus Detection and Isolation from Swine
05:59

Nasal Wipes for Influenza A Virus Detection and Isolation from Swine

Published on: December 4, 2015

9.5K

Area of Science:

  • Epidemiology
  • Virology
  • Public Health

Background:

  • Influenza A(H1N1)pdm09 and A(H3N2) are significant causes of seasonal epidemics.
  • Understanding the epidemiological differences between these strains is crucial for public health interventions.

Purpose of the Study:

  • To compare key epidemiological parameters of influenza A(H1N1)pdm09 and A(H3N2) epidemics.
  • To analyze trends in morbidity, hospitalization, and mortality across different age groups and risk factors.

Main Methods:

  • Analysis of influenza epidemic data from 59 cities (2009-2017).
  • Comparison of 4 epidemics dominated by influenza A(H1N1)pdm09 and 4 by influenza A(H3N2).
  • Examination of morbidity, hospitalization, and mortality rates, stratified by age and comorbidities.

Main Results:

  • Influenza A(H1N1)pdm09 epidemic intensity decreased; A(H3N2) intensity increased.
  • A(H1N1)pdm09 led to decreased overall incidence and mortality, but increased rates in those over 65.
  • A(H3N2) showed a more pronounced increase in morbidity and mortality among individuals over 65.
  • Lethality increased in specific risk groups for both strains, with notable increases in those over 65 and individuals with cardiovascular diseases for A(H1N1)pdm09.

Conclusions:

  • Influenza A(H1N1)pdm09 epidemics have become less severe overall but pose a greater risk to the elderly.
  • Influenza A(H3N2) epidemics are increasing in intensity and disproportionately affecting older populations.
  • Pandemic influenza strains remain a significant cause of mortality, with evolving risk profiles across different viral subtypes and patient demographics.