Related Experiment Video
Updated: Aug 18, 2025
07:34
Delivery of Antibodies into the Brain Using Focused Scanning Ultrasound
Published on: July 18, 2020
3.2K
A novel bispecific antibody able to pass the blood-brain barrier and therapeutically engage within the brain
Maj Schneider Thomsen1, Torben Moos1
1Neurobiology Research and Drug Delivery, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
Med (New York, N.Y.)
|December 10, 2022
Abstract:
The use of therapeutic antibodies for treating diseases in the CNS is hampered by the blood-brain barrier (BBB). In this issue, Edavettal et al.1 report on a novel bioengineered antibody not only capable of passing the BBB but also for intervening in pathological protein deposition and subsequent induction of clearing by microglia.
