Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantitative Analysis of Bisphenol A in Commercial Beverages.

Molecules (Basel, Switzerland)·2026
Same author

A Novel Fiber-Optical Fabry-Perot Microtip Sensor for 2-Propanol.

Sensors (Basel, Switzerland)·2025
Same author

Interrogation Method with Temperature Compensation Using Ultra-Short Fiber Bragg Gratings in Silica and Polymer Optical Fibers as Edge Filters.

Sensors (Basel, Switzerland)·2023
Same author

Fiber Bragg Grating Sensors for Reinforcing Bar Slippage Detection and Bond-Slip Gradient Characterization.

Sensors (Basel, Switzerland)·2022
Same author

Sensing System Based on FBG for Corrosion Monitoring in Metallic Structures.

Sensors (Basel, Switzerland)·2022
Same author

Optical Fiber Sensor for Monitoring the Evaporation of Ethanol-Water Mixtures.

Sensors (Basel, Switzerland)·2022

Related Experiment Video

Updated: Aug 17, 2025

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor
07:28

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Published on: August 30, 2012

10.9K

Real-Time Measurement of Refractive Index Using 3D-Printed Optofluidic Fiber Sensor.

João M Leça1, Yannis Magalhães1, Paulo Antunes1

  • 1i3N & Physics Department, University of Aveiro, Campus Universitario de Santiago, 3810-193 Aveiro, Portugal.

Sensors (Basel, Switzerland)
|December 11, 2022
PubMed
Summary

A novel 3D-printed optofluidic fiber sensor enables real-time refractive index measurement. This innovative device offers high sensitivity and stability for dynamic analyses with minimal sample consumption.

Keywords:
Fabry–Perotoptofluidicsreal-time measurementrefractive index

More Related Videos

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics
09:54

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics

Published on: September 10, 2018

7.5K
Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
08:12

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

12.9K

Related Experiment Videos

Last Updated: Aug 17, 2025

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor
07:28

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Published on: August 30, 2012

10.9K
Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics
09:54

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics

Published on: September 10, 2018

7.5K
Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
08:12

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

12.9K

Area of Science:

  • Optofluidics
  • Sensor Technology
  • Biomedical Engineering

Background:

  • Refractive index sensing is crucial for various applications, including chemical analysis and disease diagnostics.
  • Traditional methods often require complex setups and significant sample volumes.
  • Integrating microfluidics with optical fiber sensors offers a promising avenue for miniaturized and efficient sensing platforms.

Purpose of the Study:

  • To develop and characterize a 3D-printed optofluidic fiber sensor for real-time refractive index (RI) measurement.
  • To demonstrate the sensor's capability for dynamic analysis using minimal sample volumes.
  • To assess the sensor's sensitivity, stability, and resolution.

Main Methods:

  • Fabrication of a microfluidic chip platform using 3D printing.
  • Integration of an optical fiber extrinsic Fabry-Perot interferometer (EFPI) into the microfluidic chip.
  • Characterization of the optofluidic sensor using glucose solutions of varying concentrations.
  • Real-time monitoring of optical power shift correlated with RI changes.

Main Results:

  • The optofluidic fiber sensor achieved a high sensitivity of -86.6 dB/RIU with excellent linearity (r² = 0.996).
  • The sensor demonstrated good stability, with a maximum standard deviation of 0.03 dB.
  • A sensor resolution of 5.2 × 10⁻⁴ RIU was achieved, enabling precise measurements.
  • Real-time measurements confirmed the sensor's feasibility for dynamic RI analysis with low sample usage (approx. 3.7 µL/s).

Conclusions:

  • The 3D-printed optofluidic fiber sensor is a viable tool for real-time refractive index monitoring.
  • The developed platform offers a cost-effective, sensitive, and stable solution for various sensing applications.
  • This technology holds potential for applications requiring rapid analysis of small sample volumes, such as point-of-care diagnostics.