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Advances in brain-heart syndrome: Attention to cardiac complications after ischemic stroke
1Department of Cardiothoracic Surgery, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Insights
Stroke-heart syndrome (SHS) involves brain damage affecting the heart. Understanding SHS mechanisms is crucial for treating cardiac complications after ischemic stroke.
Area of Science:
- Neurocardiology: The study of brain-heart interactions.
- Investigating the impact of neurological damage on cardiac function.
Background:
- Acute ischemic stroke frequently causes cardiac complications, a leading cause of mortality post-stroke.
- Current understanding and treatment strategies for stroke-heart syndrome (SHS) remain unclear.
Purpose of the Study:
- To elucidate the clinical features and underlying mechanisms of cardiac complications following ischemic stroke.
- To provide a comprehensive overview of stroke-heart syndrome (SHS).
Main Methods:
- Review of clinical features associated with cardiac complications after ischemic stroke.
- Exploration of potential pathophysiological mechanisms, including autonomic and microvascular dysfunction.
Main Results:
- Cardiac complications are a significant cause of death following ischemic stroke.
- Autonomic dysfunction, microvascular dysfunction, and coronary ischemia are key interdependent factors in SHS.
Conclusions:
- Stroke-heart syndrome (SHS) presents a complex interplay between neurological and cardiac events.
- A comprehensive understanding of SHS is essential for advancing clinical diagnosis and treatment strategies.
Abstract:
Neurocardiology is an emerging field that studies the interaction between the brain and the heart, namely the effects of heart injury on the brain and the effects of brain damage on the heart. Acute ischemic stroke has long been known to induce heart damage. Most post-stroke deaths are attributed to nerve damage, and cardiac complications are the second leading cause of death after stroke. In clinical practice, the proper interpretation and optimal treatment for the patients with heart injury complicated by acute ischemic stroke, recently described as stroke-heart syndrome (SHS), are still unclear. Here, We describe a wide range of clinical features and potential mechanisms of cardiac complications after ischemic stroke. Autonomic dysfunction, microvascular dysfunction and coronary ischemia process are interdependent and play an important role in the process of cardiac complications caused by stroke. As a unique comprehensive view, SHS can provide theoretical basis for research and clinical diagnosis and treatment.
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