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Updated: Aug 17, 2025

A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts
Published on: February 17, 2023
An Unusual Genetic Observation in a Case of Short-Coupled PVC-Triggered Ventricular Fibrillation
Sunandan Sikdar1, Debabrata Bera2, Kapil Kumawat3
1Narayana Multispeciality Hospital, Kolkata, India.
Abstract:
Ventricular fibrillation induced by short-coupled premature ventricular complex is an uncommon cause of cardiac arrest in young individuals with no structural heart disease. The genetic substrate of this condition is heterogeneous and remains incompletely defined. We describe a case of short-coupled premature ventricular complex-triggered ventricular fibrillation with a likely pathogenic variant in the titin (TTN) gene. (Level of Difficulty: Advanced.).
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