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Related Experiment Video

Updated: Aug 17, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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Investigating informed choice in screening programmes: a mixed methods analysis.

Natalie Tyldesley-Marshall1, Amy Grove2,3, Iman Ghosh1

  • 1Applied Research Collaboration West Midlands, Warwick Medical School, University of Warwick, CV4 7AL, Coventry, UK.

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|December 12, 2022
PubMed
Summary

Achieving informed choice in screening programs presents a dilemma: prioritizing full understanding may reduce participation rates. Organizations must choose between maximizing uptake or informed decision-making for breast cancer and fetal anomaly screening.

Keywords:
CancerDecision aidsDecision-makingFetal anomaliesHealth communicationInformed choiceMixed methodsNon-invasive pregnancy testingPublic policyScreening

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Area of Science:

  • Health Services Research
  • Medical Decision Making
  • Public Health

Background:

  • Screening programs aim to identify individuals at higher risk for diseases.
  • Global consensus exists on informing screening participants, but methods vary.
  • This study examined informed choice in breast cancer and fetal anomaly screening across eight countries.

Purpose of the Study:

  • To understand how countries facilitate informed choice in screening programs.
  • To identify challenges in achieving informed choice through decision aids.

Main Methods:

  • A mixed-methods study was conducted across eight countries.
  • Interviews with 14 senior employees from decision aid organizations.
  • Documentary analysis of 15 decision aids used in screening.

Main Results:

  • Decision aids create tensions between informed choice and screening uptake.
  • Informed choice conflicts with information comprehensibility.
  • These tensions were evident in both interviews and documentary analysis.

Conclusions:

  • Organizations must prioritize either high screening uptake or maximized informed choice.
  • Information development and distribution should align with the chosen aim.
  • Prioritizing informed choice may reduce the comprehensibility of decision aids.