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Modelling mood updating: a proof of principle study
James E Clark1, Stuart Watson2
1Translational and Clinical Research Institute, Newcastle University, UK.
The British Journal of Psychiatry : the Journal of Mental Science
|December 13, 2022
Summary
This study models mood as an expectation of interoceptive consequences, using computational psychiatry to explain mood changes in depression, mania, and anxiety by adjusting prior beliefs.
Area of Science:
- Computational psychiatry
- Neuroscience
- Affective science
Background:
- Mood is hypothesized as an expectation of interoceptive consequences of actions.
- This aligns with brain function models minimizing sensory prediction error (free energy).
Purpose of the Study:
- To present a computational model of mood updating.
- To explore how altered prior beliefs influence mood in psychiatric conditions.
Main Methods:
- Utilizing a partial observable Markov decision process.
- Modeling mood changes in response to environmental stressors by minimizing prediction error.
Main Results:
- Demonstrated how altering prior beliefs can model mood states in depression, mania, and anxiety.
- Provided a computational framework for understanding mood and psychopathology.
Conclusions:
- These models offer a computational account of mood and related disorders.
- The approach can generate hypotheses for experimental research and predict disease trajectories.
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