Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Alzheimer's Disease: Treatment

Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...

CNS Depressants: Alcohol and Nicotine

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...

Substance Use Disorders Affecting Sleep

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...

Alzheimer's Disease: Overview

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...

Depressants

Depressants

Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...

Aging

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Misuse of opioid analgesics in elderly patients: a review.

Geriatrie et psychologie neuropsychiatrie du vieillissement·2021

Same author

[Substance use disorders and addictions among carers].

Soins; la revue de reference infirmiere·2020

Same author

[Analgesic opioids misuse in the elderly: A review].

Geriatrie et psychologie neuropsychiatrie du vieillissement·2020

Same author

[Day hospitalisation in addictology].

Soins. Psychiatrie·2019

Same author

[Medicines and elderly patients: abuse, dependency or attraction?]

Soins. Gerontologie·2017

Same author

[Alcohol intoxication in old age].

Soins. Gerontologie·2017

Search research articles

Related Experiment Video

Updated: Aug 17, 2025

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

[Identifying and treating alcohol use disorders in the elderly].

Pascal Menecier¹, Perrine Broyer²

¹Praticien hospitalier, service d'addictologie, CH Les Chanaux, Mâcon, France ; docteur en psychologie, institut de psychologie, université Lumière- Lyon-2, Bron, France, équipe de recherche DIPHE.

La Revue Du Praticien

|December 13, 2022

Summary

Alcohol use disorders are common in older adults and pose significant health risks, often going undiagnosed. Early screening and adapted treatment strategies lead to positive outcomes for elderly patients.

Keywords:

Aged Alcoholism

More Related Videos

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Published on: January 7, 2019

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Related Experiment Videos

Last Updated: Aug 17, 2025

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Published on: January 7, 2019

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Area of Science:

Gerontology
Addiction Medicine
Public Health

Context:

Alcohol use disorders (AUDs) persist in older populations, with age exacerbating risks.
Comorbidities and polypharmacy in the elderly amplify alcohol-related harm.
AUDs in older adults are frequently undiagnosed until complications arise.

Purpose:

To highlight the prevalence and risks of alcohol use disorders in the elderly.
To emphasize the need for systematic screening and adapted care strategies.
To underscore the positive prognosis for treating AUDs in older individuals.

Summary:

Aging does not eliminate alcohol use disorders; it increases susceptibility to alcohol's adverse effects.
Polypathology and polypharmacy in the elderly heighten risks associated with alcohol consumption.
Undiagnosed AUDs in older adults often present with severe complications, necessitating proactive identification.

Impact:

Systematic screening is crucial for early detection of AUDs in the elderly.
Adapted treatment approaches offer a good to excellent prognosis for older individuals with AUDs.
Recognizing and addressing AUDs in aging populations improves health outcomes and reduces healthcare burdens.