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Updated: Aug 17, 2025
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
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Prevention of Migraine.
Ashley Holdridge1, Jennifer Buczyner2, Cristina Cabret Aymat3
1Department of Neurology and Headache, Advocate Aurora HealthCare, Whitefish Bay, Wisconsin.
Seminars in Neurology
|December 13, 2022
Summary
New migraine prevention strategies, including CGRP antagonists and neurostimulation, offer improved treatment options for this chronic neurological condition. These advances, alongside OnabotulinumtoxinA and lifestyle changes, are transforming migraine management.
Area of Science:
- Neurology
- Neuroscience
- Pharmacology
Background:
- Migraine is a prevalent, chronic neurological disorder significantly impacting global quality of life.
- It is a leading cause for physician consultations and specialist referrals in neurology.
Purpose of the Study:
- To review recent advancements in migraine pathophysiology.
- To highlight novel therapeutic and preventive strategies for migraine management.
Main Methods:
- Review of recent scientific literature on migraine treatment and prevention.
- Analysis of emerging therapeutic classes and non-pharmacologic approaches.
Main Results:
- Calcitonin gene-related peptide antagonists (CGRP-A) represent a significant advancement in preventive migraine therapy.
- OnabotulinumtoxinA (BoNTA) continues to be a key treatment for chronic migraine, with emerging combination therapy data.
- Neurostimulation provides a non-pharmacologic avenue for migraine treatment.
Conclusions:
- Recent therapeutic innovations have substantially altered the landscape of migraine prevention.
- A multimodal approach combining pharmacologic and non-pharmacologic strategies, alongside lifestyle modifications, is key to effective migraine management.
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