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Updated: Aug 17, 2025

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
[Multidisciplinary approach to fracture-related infection]
Quentin Muller1,2, Filippo Gerber1, Matthaios Papadimitriou Olivgeris3
1Service d'orthopédie et de traumatologie, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Abstract:
Fracture-related infection is a feared complication of trauma surgery with potentially major repercussions on quality of life and healthcare systems. Its management is based on two pillars: a radical surgical debridement along with a targeted long-term antibiotic therapy based on multiple deep tissue samples obtained during the chosen surgical procedure. Multidisciplinary management and early diagnosis are essential for treatment success. The implementation of a standardized definition for fracture-related infections since 2018 has allowed the optimization and streamlining of management algorithms and their validation in the literature. This article provides a comprehensive and in-depth review of recent advances in the diagnosis and management of fracture-related infections.
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