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Area of Science:

  • Natural Language Processing
  • Computational Linguistics
  • Pharmacovigilance

Background:

  • Drug review websites offer user-generated text and numeric ratings.
  • Numeric ratings may not align with textual sentiment, impacting reliability.
  • Automated classification of drug review text can enhance rating accuracy.

Purpose of the Study:

  • To develop and compare machine learning models for classifying drug review ratings based on textual content.
  • To evaluate the performance of traditional and deep learning models, including transformer networks.
  • To identify medical concepts within reviews and analyze their semantic types.

Main Methods:

  • Utilized traditional machine learning (Random Forest, Naive Bayesian) with TF-IDF features.
  • Implemented transformer-based deep learning models (BERT, Bio_ClinicalBERT, RoBERTa, XLNet, ELECTRA, ALBERT) using raw text.
  • Applied Unified Medical Language System (UMLS) concept identification and semantic type analysis.

Main Results:

  • The Bio_ClinicalBERT model achieved the highest accuracy at 87%.
  • Transformer-based models demonstrated effectiveness in classifying drug reviews solely from text.
  • Analysis of UMLS concepts provided insights into review content stratified by predicted sentiment.

Conclusions:

  • Transformer models are highly effective for automated drug review classification.
  • Text-based classification offers a more reliable alternative to solely relying on numeric ratings.
  • This approach can improve the understanding of public drug perception and pharmacovigilance.