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Incremental lines in human cellular cementum: A histological study.

Shizuka Takahashi1, Tsuneyuki Yamamoto2, Tomomi Takahashi3

  • 1Dentistry for Children and Disabled Persons, Department of Oral Functional Science, Faculty of Dental Medicine, Hokkaido University, Kita13 Nishi7, Kita-ku, Sapporo 060-8586, Japan.

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Summary

Human cellular cementum

Keywords:
Cellular cementumContact microradiographyIncremental linesScanning electron microscopy

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Area of Science:

  • Biomaterials Science
  • Dental Histology
  • Cellular Biology

Background:

  • Human cellular cementum exhibits incremental lines that define cementum lamellae.
  • The precise structure and function of these lines are not fully understood.

Purpose of the Study:

  • To investigate the ultrastructure of incremental lines in human cellular cementum.
  • To clarify the role of these lines in cellular cementogenesis.

Main Methods:

  • Examination of human mandibular molars using light microscopy, scanning electron microscopy, and contact microradiography.
  • Preparation of longitudinal paraffin and ground sections with various staining techniques.

Main Results:

  • Incremental lines are collagen fibril-poor layers.
  • Cementum lamellae display an alternating structure of highly mineralized and less mineralized fibrils.
  • Incremental lines are located at the inner aspect of the less mineralized fibril regions.

Conclusions:

  • Cellular cementogenesis involves alternating low and high activity states of cementoblasts.
  • Low-activity cementoblasts produce fibril-poor, poorly mineralized incremental lines.
  • High-activity cementoblasts form the highly mineralized, alternating lamellar structure of cementum.