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Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis
07:56

Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis

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Hyperhomocysteinemia is related to large vessel occlusion in young patients with COVID-19: Two case reports

Seyedehnarges Tabatabaee1, Fatemeh Rezania2, Sevim Soleimani3

  • 1Division of Neurology Firoozgar hospital, Iran University of Medical Sciences Tehran Iran.

Clinical Case Reports
|December 16, 2022
PubMed

Insights

Two young, healthy men experienced acute ischemic stroke from large vessel occlusion after COVID-19 infection. This suggests COVID-19 may worsen underlying blood clotting disorders, increasing stroke risk.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Hematology

Background:

  • COVID-19 is a global pandemic with known cardiovascular complications.
  • Thrombophilia, a predisposition to blood clots, can increase stroke risk.
  • Young adults are typically at lower risk for ischemic stroke.

Observation:

  • Two previously healthy young men presented with acute ischemic stroke.
  • Both patients had confirmed COVID-19 infection.
  • The strokes were characterized by large vessel occlusion and signs of further thromboembolic events.

Findings:

  • COVID-19 infection was associated with acute ischemic stroke in young, healthy individuals.
  • The hypercoagulable state induced by COVID-19 may exacerbate pre-existing hereditary thrombophilia.
  • Large vessel occlusion was the primary cause of stroke in these cases.

Implications:

  • This highlights a potential mechanism linking COVID-19 to severe cerebrovascular events in susceptible individuals.
  • Early recognition and management of hypercoagulable states in COVID-19 patients may be crucial.
  • Further research is needed to understand the long-term neurological risks associated with COVID-19.

Keywords:
COVID‐19hyperhomocysteinemialarge vessel occlusionyoung stroke

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