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Bacteremia due to Neisseria cinerea: report of two cases
1Department of Pathology, University of Texas Health Science Center at Dallas 75235-9072.
Diagnostic Microbiology and Infectious Disease
|June 1, 1987
Abstract:
We report two cases of bacteremia due to Neisseria cinerea. One was a 2.5-yr-old boy with otitis media and pneumonia, who responded to treatment with amoxicillin. The other was a 47-yr-old man with underlying ethanol abuse who developed severe polymicrobial sepsis due to apparent intraabdominal disease. This man died despite extensive antimicrobial therapy.
Insights
Neisseria cinerea bacteremia is rare but can occur in children and adults. While one patient recovered with amoxicillin, another with severe sepsis did not survive.
Area of Science:
- Medical Microbiology
- Infectious Diseases
Background:
- Neisseria cinerea is a commensal bacterium of the human oropharynx.
- Bacteremia due to Neisseria cinerea is infrequently reported in clinical literature.
Observation:
- A 2.5-year-old boy presented with otitis media and pneumonia, developing bacteremia caused by Neisseria cinerea.
- A 47-year-old man with a history of ethanol abuse developed severe polymicrobial sepsis, with Neisseria cinerea identified as a causative agent, likely from intraabdominal disease.
Findings:
- The pediatric patient with Neisseria cinerea bacteremia and otitis media/pneumonia demonstrated a positive response to amoxicillin treatment.
- Despite aggressive antimicrobial interventions, the adult patient with severe polymicrobial sepsis and Neisseria cinerea bacteremia succumbed to the infection.
Implications:
- These cases highlight the potential pathogenicity of Neisseria cinerea, particularly in immunocompromised or critically ill individuals.
- Understanding the clinical spectrum and treatment outcomes of Neisseria cinerea bacteremia is crucial for effective patient management.