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Updated: Aug 16, 2025

Preparation and Reactivity of a Triphosphenium Bromide Salt: A Convenient and Stable Source of PhosphorusI
Published on: November 22, 2016
Endo-Functionalized Cyclic Oligophenylenes: Synthesis and Complexation with a Chiral Phosphoric Acid
Kosuke Ono1, Yusei Tanaka1, Kana Sugimoto1
1Department of Chemistry, Faculty of Science, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan.
Abstract:
The synthesis of endo-functionalized cyclic oligophenylenes in which adjacent benzene rings are perpendicular to one another is described. Annulation precursors, OH- or NH2-functionalized quinquephenyl diboronic acids, and septiphenyl dibromo compounds were systematically prepared by using a diprotected biphenyl-3,4'-diyl diboronic acid as a key compound. Four endo-functionalized cyclic oligophenylenes were synthesized by annulation of the precursors in dilute conditions through Suzuki-Miyaura cross-coupling. X-ray analysis of the macrocycle revealed the unique 1D channel packing structure formed by connecting the nanometer-sized cavity of the macrocycle. Furthermore, NH2-functionalized macrocycles could bind a chiral phosphoric acid in the cavity in CDCl3 solution.
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