Pseudo-Meigs syndrome secondary to endodermal sinus tumor

Area of Science:

• Gynecologic Oncology
• Pediatric Oncology
• Pathology

Background:

• Ovarian tumors are common in girls, with germ cell tumors accounting for 60-70%.
• Pseudo-Meigs syndrome presents as a pelvic mass, pleural effusion, and ascites, resolving after mass removal.
• Endodermal sinus (yolk sac) tumors are an exceptionally rare etiology for Pseudo-Meigs syndrome.

Purpose of the Study:

• To report a rare case of Pseudo-Meigs syndrome caused by an endodermal sinus (yolk sac) tumor in a girl.
• To contribute to the limited literature on this specific tumor type and syndrome presentation.

Main Methods:

• Case report detailing clinical presentation, diagnostic workup, and pathological findings.
• Review of relevant literature on Pseudo-Meigs syndrome and yolk sac tumors.

Main Results:

• The patient presented with classic symptoms of Pseudo-Meigs syndrome.
• Pathological diagnosis confirmed the presence of a yolk sac tumor.
• Surgical intervention led to the resolution of ascites and pleural effusion.

Conclusions:

• Endodermal sinus (yolk sac) tumors, though rare, should be considered in the differential diagnosis of Pseudo-Meigs syndrome in pediatric patients.
• This case underscores the importance of thorough pathological evaluation for accurate diagnosis and management.