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Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...

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Related Experiment Video

Updated: Aug 16, 2025

Formation of Human Periodontal Ligament Cell Spheroids on Chitosan Films

Formation of Human Periodontal Ligament Cell Spheroids on Chitosan Films

Published on: June 19, 2019

Periodontal ligament stem cell-based bioactive constructs for bone tissue engineering.

Zeqing Zhao¹, Jin Liu², Michael D Weir³

¹Department of Orthodontics, School of Stomatology, Capital Medical University, Beijing, China.

Frontiers in Bioengineering and Biotechnology

|December 19, 2022

Summary

This summary is machine-generated.

Periodontal ligament stem cells (PDLSCs) show great potential for regenerating bone and periodontal tissues. Combining PDLSCs with various materials and strategies enhances their effectiveness in tissue engineering applications.

Keywords:

bone regeneration periodontal ligament stem cells periodontal tissue regeneration scaffold tissue engineering

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Last Updated: Aug 16, 2025

Formation of Human Periodontal Ligament Cell Spheroids on Chitosan Films

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Published on: June 19, 2019

Use of Human Perivascular Stem Cells for Bone Regeneration

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Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells

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Published on: May 4, 2018

Area of Science:

Biomaterials Science
Regenerative Medicine
Stem Cell Biology

Background:

Stem cell-based tissue engineering offers promising solutions for bone repair.
Periodontal ligament stem cells (PDLSCs) are a valuable cell source for maxillofacial and periodontal regeneration.

Purpose of the Study:

To review recent advancements in PDLSC-based bone and periodontal tissue regeneration.
To highlight cutting-edge research in PDLSC applications for tissue engineering.

Main Methods:

Extensive literature search on PubMed, Medline, and Google Scholar for PDLSC-based bioactive constructs.
Selection of relevant papers by three independent reviewers.

Main Results:

PDLSCs combined with xenogeneic bone grafts, calcium phosphates, and polymers show potential for regeneration.
Osteoinductive agents, gene therapy, physical stimulation, and co-culture strategies enhance PDLSC efficacy.

Conclusions:

PDLSC-based bioactive constructs represent a promising strategy for bone and periodontal tissue regeneration.
Further research into PDLSC applications can advance regenerative medicine.