Therapy for Stage IV Non-Small-Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline, Version 2022.2

Area of Science:

• Clinical Practice Guidelines
• Evidence-Based Medicine
• Medical Literature Review

Background:

• Rapidly evolving evidence necessitates frequent updates in clinical practice.
• Living guidelines address areas where medical knowledge changes quickly.
• Existing guidelines may become outdated due to the pace of research.

Purpose of the Study:

• To describe the development and methodology of living guidelines.
• To explain the process of continuous literature review for guideline updates.
• To outline the framework for the American Society of Clinical Oncology (ASCO) Living Guidelines.

Main Methods:

• Systematic, continuous review of health literature by a standing expert panel.
• Regularly scheduled updates to reflect the latest evidence.
• Adherence to the ASCO Guidelines Methodology Manual and Conflict of Interest Policy.

Main Results:

• Living guidelines offer a dynamic approach to clinical recommendations.
• Regular updates ensure that practice recommendations are current.
• The ASCO Living Guidelines provide a structured methodology for this process.

Conclusions:

• Living guidelines are essential for managing rapidly changing medical evidence.
• Continuous review and regular updates are key features.
• These guidelines support evidence-based clinical decision-making.