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The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
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A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
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Weighted Heterogeneous Graph-Based Incremental Automatic Disease Diagnosis Method.

Yuanyuan Tian1, Yanrui Jin1, Zhiyuan Li1

  • 1State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, 200240 China.

Journal of Shanghai Jiaotong University (Science)
|December 21, 2022
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Summary
This summary is machine-generated.

This study introduces an experience-infused knowledge model using incremental learning and knowledge graphs for automatic diagnosis. The novel approach enhances diagnostic accuracy and resists forgetting, outperforming classical models.

Keywords:
adaptive neural networkdisease diagnosisincremental learningknowledge graphknowledge model

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Area of Science:

  • Artificial Intelligence
  • Medical Informatics
  • Knowledge Representation

Background:

  • Automatic diagnosis models face challenges in classifying numerous diseases and collecting extensive disease-symptom datasets.
  • Existing models struggle with scalability and data acquisition for comprehensive diagnostic capabilities.

Purpose of the Study:

  • To develop an experience-infused knowledge model for multi-department symptom-based automatic diagnosis.
  • To address data collection limitations and large-scale multi-classification issues using knowledge graphs and incremental learning.

Main Methods:

  • Constructed a heterogeneous knowledge graph via graph fusion and entity linking.
  • Employed incremental learning to continuously update the knowledge graph with experiential knowledge from data.
  • Developed adaptive neural network models for each dataset, integrating learned parameters back into the knowledge graph.

Main Results:

  • The proposed model demonstrated improved diagnostic accuracy across three public datasets, with average improvements of 5%, 2%, and 15%.
  • The model exhibited a strong ability to resist forgetting, maintaining performance on historical data after class increments.
  • Incremental learning effectively addressed data collection challenges and enabled scalable multi-classification.

Conclusions:

  • The experience-infused knowledge model offers a robust solution for automatic diagnosis, overcoming limitations of traditional approaches.
  • Incremental learning and knowledge graph integration are effective strategies for building adaptive and accurate diagnostic systems.
  • The model shows significant potential for enhancing clinical decision support systems through continuous learning and knowledge integration.