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Intracranial Corkscrew Angiopathy.

Rakhee Lalla1, Deepti Virmani1, Kushak Suchdev1

  • 1Department of Neurology (RL, DV, KS, MA, TNN), Boston Medical Center; and Department of Ophthalmology (CEP), Boston Medical Center.

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Summary

A rare case of corkscrew cerebral angiopathy presenting as subarachnoid hemorrhage (SAH) was identified. This unusual presentation in a young woman resolved without neurological deficits.

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Area of Science:

  • Neurology
  • Vascular Neurology
  • Neuroimaging

Background:

  • Subarachnoid hemorrhage (SAH) typically results from ruptured aneurysms.
  • Corkscrew cerebral angiopathy is a rare vascular condition.
  • Non-aneurysmal SAH requires thorough investigation into underlying causes.

Purpose of the Study:

  • To report a rare case of corkscrew cerebral angiopathy.
  • To describe its presentation as subarachnoid hemorrhage (SAH).
  • To highlight diagnostic findings and clinical course.

Main Methods:

  • Case report of a young woman with thunderclap headache.
  • Diagnostic workup included cerebral angiography.
  • Exclusionary testing for vasculitis and genetic causes.

Main Results:

  • Cerebral angiogram showed corkscrew angiopathy in medium-sized vessels and micro-occlusions.
  • No intracranial aneurysm was identified.
  • Extensive workup for vasculitis and genetic causes was negative; symptoms resolved without deficits.

Conclusions:

  • Corkscrew cerebral angiopathy is an extremely rare cause of subarachnoid hemorrhage (SAH).
  • This case underscores the importance of considering rare etiologies in non-aneurysmal SAH.
  • Prompt diagnosis and management are crucial for favorable outcomes.