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Vascular complications in 305 severely ill patients with COVID-19: a cohort study

Rebeca Mangabeira Correia1, Brena Costa Santos1, Ana Alyra Garcia Carvalho1

  • 1MD. Master's Student, Division of Vascular and Endovascular Surgery, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), São Paulo, Brazil.

Sao Paulo Medical Journal = Revista Paulista De Medicina
|December 21, 2022
PubMed

Insights

Vascular complications, including disseminated intravascular coagulation and acrocyanosis, were common in critically ill COVID-19 patients. These complications were significantly associated with a higher mortality rate within 30 days of ICU admission.

Area of Science:

  • Critical Care Medicine
  • Vascular Medicine
  • Infectious Diseases

Background:

  • Limited data exist on vascular complications beyond venous thromboembolism in COVID-19 patients.
  • Understanding these complications is crucial for managing severely ill individuals.

Purpose of the Study:

  • To investigate the incidence of vascular complications in critically ill COVID-19 patients.
  • To determine the association between these complications and all-cause mortality.

Main Methods:

  • A cohort study included 305 consecutive COVID-19 patients admitted to the ICU.
  • Patients were followed for 30 days post-admission.
  • Data on vascular complications and mortality were collected.

Main Results:

  • The overall mortality rate was 56.3%.
  • Vascular complications occurred in 23.6% of patients, more frequently in non-survivors (28.5%) than survivors (17.3%).
  • Disseminated intravascular coagulation (DIC) and acrocyanosis were significantly associated with higher mortality.

Conclusions:

  • Vascular complications are frequent in critically ill COVID-19 patients and linked to mortality.
  • Identifying and managing these complications is vital for improving outcomes in severe COVID-19 cases.
Abstract

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