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Case Report: Interventional therapy for coronary artery occlusion in a 6-year-old child with Kawasaki disease
Lu Zhao1, Li-Ping Xie1, Lan He1
1Department of Cardiology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Insights
A pediatric patient with Kawasaki disease and coronary artery aneurysms underwent successful recanalization of a blocked left circumflex artery. This percutaneous coronary intervention demonstrated good blood flow, offering a viable treatment option for select cases.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Interventional Cardiology
Background:
- Kawasaki disease can lead to coronary artery aneurysms and complications like myocardial ischemia.
- Giant coronary artery aneurysms pose significant risks, including vessel occlusion.
Observation:
- A 6-year-old girl with a history of Kawasaki disease presented with chest pain and ECG changes.
- Stress myocardial perfusion imaging revealed reversible left ventricular ischemia.
- Coronary angiography identified a complete proximal occlusion of the left circumflex artery (LCX).
Findings:
- Successful recanalization of the occluded LCX was achieved using a micro-wire.
- Sequential balloon dilation and drug-coated balloon angioplasty were performed.
- Post-intervention and one-year follow-up angiography confirmed good LCX structure and blood flow.
Implications:
- Percutaneous coronary intervention (PCI) is a feasible treatment for selected pediatric patients with Kawasaki disease and coronary artery occlusion.
- This case highlights the potential of interventional techniques in managing complex coronary artery complications in children.
- Successful PCI may prevent adverse cardiac events in pediatric patients with Kawasaki disease-associated coronary aneurysms.
Abstract:
A 6-year-old girl was diagnosed with Kawasaki disease and bilateral giant coronary artery aneurysms at four months old and was subsequently referred to our hospital due to chest pain and T wave changes on electrocardiography. After admission, stress myocardial perfusion imaging showed reversible ischemia in multiple areas of the left ventricle. Coronary angiography revealed complete proximal segment occlusion of the left circumflex artery (LCX). The occluded LCX was recanalized by a Gaia 3rd micro-wire successfully passing through the occluded section to the distal end of the LCX, followed by sequential balloon dilation and drug-coated balloon angioplasty. Coronary angiography immediately after post-dilation and one-year follow-up angiography showed that the structure and blood flow of LCX was good. Although percutaneous coronary intervention (PCI) in pediatric patients with Kawasaki disease is limited in practice, PCI remains one of the treatment options for selected patients.
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