Case Report: Interventional therapy for coronary artery occlusion in a 6-year-old child with Kawasaki disease

Lu Zhao1, Li-Ping Xie1, Lan He1

  • 1Department of Cardiology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.

Frontiers in Pediatrics
|December 22, 2022
PubMed

Insights

A pediatric patient with Kawasaki disease and coronary artery aneurysms underwent successful recanalization of a blocked left circumflex artery. This percutaneous coronary intervention demonstrated good blood flow, offering a viable treatment option for select cases.

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Interventional Cardiology

Background:

  • Kawasaki disease can lead to coronary artery aneurysms and complications like myocardial ischemia.
  • Giant coronary artery aneurysms pose significant risks, including vessel occlusion.

Observation:

  • A 6-year-old girl with a history of Kawasaki disease presented with chest pain and ECG changes.
  • Stress myocardial perfusion imaging revealed reversible left ventricular ischemia.
  • Coronary angiography identified a complete proximal occlusion of the left circumflex artery (LCX).

Findings:

  • Successful recanalization of the occluded LCX was achieved using a micro-wire.
  • Sequential balloon dilation and drug-coated balloon angioplasty were performed.
  • Post-intervention and one-year follow-up angiography confirmed good LCX structure and blood flow.

Implications:

  • Percutaneous coronary intervention (PCI) is a feasible treatment for selected pediatric patients with Kawasaki disease and coronary artery occlusion.
  • This case highlights the potential of interventional techniques in managing complex coronary artery complications in children.
  • Successful PCI may prevent adverse cardiac events in pediatric patients with Kawasaki disease-associated coronary aneurysms.

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