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Experimental Animal Models: Tools to Investigate Antidiabetic Activity
Rashmi Madhariya1, Bhupendra Dixena1, Alpana Ram1
1Department of Pharmacy, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (C.G.), 495009, India.
Current Pharmaceutical Design
|December 22, 2022
Summary
This review summarizes animal models for studying diabetes mellitus, a metabolic disorder affecting 2.8% of the global population. Understanding these models is crucial for developing effective anti-diabetic drugs and treatments.
Area of Science:
- Endocrinology and Metabolism
- Pharmacology
- Animal Models in Research
Background:
- Diabetes mellitus is a global health concern affecting approximately 2.8% of the population, characterized by hyperglycemia due to insulin deficiency.
- Current research focuses on developing more effective anti-diabetic drugs to manage this complex metabolic disorder.
- Various animal models, chemicals, and diabetogenic hormones are employed to study diabetes mellitus and evaluate potential therapeutic interventions.
Conclusions:
- Appropriate selection of animal models, based on their similarities to human diabetes, is critical for advancing our understanding of disease mechanisms.
- These models are essential tools for evaluating the efficacy of existing and novel anti-diabetic drugs.
- Further research utilizing well-characterized animal models will facilitate the development of targeted therapies for diabetes mellitus.
