Atrophic Dermatofibrosarcoma Protuberans with Eosinophilic Infiltration

Area of Science:

• Dermatopathology
• Oncology

Background:

• Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive skin tumor.
• It typically affects the trunk and proximal extremities, with acral involvement being uncommon.

Observation:

• Atrophic DFSP, a morphologically distinct variant of DFSP, commonly affects young adults.
• The standard treatment involves surgical excision and long-term monitoring for recurrence.

Findings:

• This report presents an exceptionally rare case of atrophic DFSP.
• The case is distinguished by the presence of eosinophilic infiltration, a feature documented in only one prior instance.

Implications:

• This case expands the understanding of DFSP variations.
• It underscores the importance of recognizing rare presentations for accurate diagnosis and management of dermatofibrosarcoma protuberans.