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Hyponatremia As A Marker Of Complicated Appendicitis
Muhammad Umer Qureshi1, Asad Iqbal1, Murad Habib1
1Department of Paediatric surgery, The children hospital, Pakistan Institute of Medical Sciences, Islamabad.
Journal of Ayub Medical College, Abbottabad : JAMC
|December 23, 2022
Summary
Low serum sodium levels may indicate complicated appendicitis in children. This hyponatremia marker helps differentiate between uncomplicated and complicated appendicitis, offering a low-cost diagnostic tool.
Area of Science:
- Pediatric Surgery
- Clinical Chemistry
Background:
- Acute appendicitis is a common cause of acute abdomen in children.
- One-third of cases progress to complicated appendicitis if not treated promptly.
- Management differs significantly between uncomplicated and complicated appendicitis.
Purpose of the Study:
- To assess the relationship between serum sodium levels and complicated appendicitis in pediatric patients.
- To evaluate hyponatremia as a potential marker for differentiating appendicitis severity.
Main Methods:
- Prospective observational study of 140 pediatric patients from July to December 2020.
- Patients divided into uncomplicated (Group 1) and complicated (Group 2) appendicitis groups.
- Comparison of preoperative serum sodium levels between the two groups.
Main Results:
- Median serum sodium was 137.81 mg/dl in uncomplicated appendicitis vs. 131.35 mg/dl in complicated appendicitis.
- Serum sodium levels < 135 mg/dl showed 84.80% sensitivity and 89.40% specificity.
- Hyponatremia emerged as a potential indicator for complicated appendicitis.
Conclusions:
- Hyponatremia is proposed as a novel marker for differentiating complicated from uncomplicated appendicitis in children.
- Serum sodium levels offer a low-cost, high-efficiency predictive marker for diagnosis and differentiation.
- This finding may aid in timely and appropriate management of pediatric appendicitis.
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