Related Experiment Video
Updated: Aug 16, 2025

08:05
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
14.3K
Air Leak Syndrome In Patients With Severe Covid Pneumonia
Arshi Naz1, Basma Salman1, Sidra Javed1
1Shaheed Mohtarma Benazir Bhutto Institute of Trauma, Karachi, Pakistan.
Journal of Ayub Medical College, Abbottabad : JAMC
|December 23, 2022
Summary
Emerging studies link air leak syndrome (ALS) with COVID-19, but data is scarce. This study found a high mortality rate of 84.5% in severe COVID-19 patients experiencing air leaks.
Area of Science:
- Pulmonology
- Infectious Diseases
- Critical Care Medicine
Background:
- Emerging evidence suggests a link between air leak syndrome (ALS) and COVID-19.
- Data regarding the association, incidence, and outcomes of ALS in COVID-19 patients remains limited.
Purpose of the Study:
- To investigate the risk factors and clinical outcomes associated with air leakage events in hospitalized COVID-19 patients.
- To understand the specific characteristics and consequences of ALS in the context of severe COVID-19 pneumonia.
Main Methods:
- A single-centered case series was conducted.
- Data was collected from COVID-19 patients admitted to SMBBIT in Karachi, Pakistan, between April 24, 2020, and June 10, 2021.
Main Results:
- Nineteen patients with severe COVID-19 pneumonia developed air leaks.
- Subcutaneous emphysema was the most common finding (94%).
- The mortality rate among these patients was high at 84.5%.
Conclusions:
- Air leak syndrome is a serious complication in severe COVID-19 pneumonia.
- The high mortality rate underscores the need for further research into risk factors and management strategies for ALS in COVID-19 patients.
Related Concept Videos
Pneumonia II: Pathophysiology
414
The pathophysiology of pneumonia involves the following steps:
414
Pneumothorax-II
260
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
260
Acute Respiratory Failure-IV
189
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
189
Pneumonia I: Introduction
300
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
300
Pneumonia III: Complications and Assessment
344
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
344
Pneumothorax-I
288
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
288

