Related Experiment Video
Updated: Jul 1, 2026

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors
Published on: February 10, 2014
Label-Free Bound-States-in-the-Continuum Biosensors
Man Luo1, Yi Zhou1, Xuyang Zhao1
1The Key Laboratory of Micro and Nano Photonic Structures, Department of Optical Science and Engineering, Fudan University, Shanghai 200438, China.
Abstract:
Bound states in the continuum (BICs) have attracted considerable attentions for biological and chemical sensing due to their infinite quality (Q)-factors in theory. Such high-Q devices with enhanced light-matter interaction ability are very sensitive to the local refractive index changes, opening a new horizon for advanced biosensing. In this review, we focus on the latest developments of label-free optical biosensors governed by BICs. These BICs biosensors are summarized from the perspective of constituent materials (i.e., dielectric, metal, and hybrid) and structures (i.e., grating, metasurfaces, and photonic crystals). Finally, the current challenges are discussed and an outlook is also presented for BICs inspired biosensors.
More Related Videos
08:22Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
Published on: February 16, 2018
09:39Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology
Published on: March 31, 2022
Related Concept Videos
Labeling DNA Probes
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
Difference from Background: Limit of Detection
The LOD indicates the presence or absence...
Microbial Biosensors