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Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain

Emily Rav1, Rachna Sheth2, Ali H Ahmad3

  • 1Pediatric Oncology Fellowship Program, Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Children (Basel, Switzerland)
|December 23, 2022
PubMed

Insights

Systemic lidocaine infusions offer a safe and effective option for managing refractory cancer pain in pediatric patients. This approach can decrease pain scores and improve the quality of life for children undergoing cancer treatment.

Area of Science:

  • Pediatric Oncology
  • Pain Management
  • Pharmacology

Background:

  • Pediatric cancer patients experience significant distress from cancer-related pain and treatment.
  • Refractory pain presents a therapeutic challenge in this population.
  • Analgesic regimen selection requires careful consideration of individual patient factors.

Purpose of the Study:

  • To review the use of systemic lidocaine infusions for analgesia in pediatric oncology patients.
  • To evaluate the safety and efficacy of lidocaine for refractory cancer pain.

Main Methods:

  • Literature review of studies on systemic lidocaine infusions in pediatric oncology.
  • Analysis of patient-reported outcomes, including pain scores and quality of life.

Main Results:

  • Systemic lidocaine infusions have demonstrated safety and efficacy in prior studies.
  • Patients reported decreased pain scores following lidocaine treatment.
  • Improved quality of life was observed in patients receiving lidocaine.

Conclusions:

  • Systemic lidocaine infusions show potential as an analgesic option for refractory pain in pediatric cancer.
  • Lidocaine's favorable side effect profile supports its consideration in this patient group.

Keywords:
analgesiacancerchildrenlidocaineoncologypainpediatrics

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