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Varietal Effect on Composition and Digestibility of Seedless Table Grapes (Vitis vinifera L.) under In Vitro
Marianela Desireé Rodríguez1,2, Joaquin García-Cordero1, Diana Suárez-Coca1
1Institute of Food Science, Technology and Nutrition (ICTAN), Spanish Research Council (CSIC), Jose Antonio Novais 6, 28040 Madrid, Spain.
Foods (Basel, Switzerland)
|December 23, 2022
Summary
Black and red grapes are rich in dietary antioxidants. This study investigated how grape variety and in vitro digestion affect polyphenol composition and bioavailability, finding that most polyphenols
Area of Science:
- Food Science
- Nutritional Biochemistry
- Plant Chemistry
Background:
- Grapes are a significant source of polyphenols and antioxidants within the Mediterranean diet.
- The increasing market for seedless grape varieties necessitates characterization of their unique compositions.
- Polyphenol bioavailability and bioactivity are influenced by in vitro digestion processes.
Purpose of the Study:
- To analyze the effect of grape variety on initial polyphenol composition.
- To determine the absorbable polyphenol fraction reaching the intestine after in vitro digestion.
- To assess the impact of digestion on the antioxidant potential of different grape varieties.
Main Methods:
- In vitro digestion model simulating human gastrointestinal conditions.
- Analysis of polyphenol profiles in grape extracts before and after digestion.
- Quantification of absorbable polyphenol fractions.
Main Results:
- Black and red grape varieties exhibit high potential for enhancing dietary antioxidant content.
- In vitro digestion significantly reduced the bioavailable fraction of most polyphenols.
- Flavanols were an exception, showing less reduction in their bioavailable fraction post-digestion.
Conclusions:
- Grape variety significantly influences polyphenol composition and post-digestion bioavailability.
- Black and red grapes are valuable sources of dietary antioxidants.
- Digestive processes, particularly in vitro, can diminish the bioavailability of various polyphenols, except flavanols.

