Jove
Visualize
Contact Us

Related Concept Videos

Bioavailability Enhancement: Drug Stability Enhancement and GI Retention01:05

Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis and Characterization of CNC/CNF/rGO Composite Films for Advanced Functional Applications.

Micromachines·2026
Same author

Lasso Model-Based Optimization of CNC/CNF/rGO Nanocomposites.

Micromachines·2025
Same author

Advancements in Hybrid Cellulose-Based Films: Innovations and Applications in 2D Nano-Delivery Systems.

Journal of functional biomaterials·2024
Same author

Advancement in Biosensor Technologies of 2D MaterialIntegrated with Cellulose-Physical Properties.

Micromachines·2024
Same author

SiCNFe Ceramics as Soft Magnetic Material for MEMS Magnetic Devices: A Mössbauer Study.

Micromachines·2023
Same author

Preparation and Characterization of Eco-Friendly Transparent Antibacterial Starch/Polyvinyl Alcohol Materials for Use as Wound-Dressing.

Micromachines·2022
Same journal

Correction: Kang et al. Fluid Flow to Electricity: Capturing Flow-Induced Vibrations with Micro-Electromechanical-System-Based Piezoelectric Energy Harvester. <i>Micromachines</i> 2024, <i>15</i>, 581.

Micromachines·2026
Same journal

Femtosecond Laser Texturing of Wood Coatings with Bio-Based Epoxy and Wax Additives for Enhanced Hydrophobicity.

Micromachines·2026
Same journal

Engineering of Optoelectronic Devices for Renewable Energy Applications.

Micromachines·2026
Same journal

Phase Transformation and Electrochemical Behavior of Hexagonal TiO<sub>2</sub> Nanotubes Under Different Annealing Temperatures and Heating Rates.

Micromachines·2026
Same journal

Process Optimization and Predictive Modeling of Femtosecond Laser Precision Milling for Commercial PMMA Slices.

Micromachines·2026
Same journal

A Hybrid Preprocessing Multi-Objective Surrogate Model for Thermal MEMS Actuators.

Micromachines·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 20, 2026

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing
04:09

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing

Published on: December 13, 2024

697

Optimizing Biodegradable Starch-Based Composite Films Formulation for Wound-Dressing Applications.

Mohammad Mohsen Delavari1, Ixchel Ocampo2, Ion Stiharu1

  • 1Department of Mechanical, Industrial, and Aerospace Engineering, Concordia University, Montreal, QC H3G 1M8, Canada.

Micromachines
|December 23, 2022
PubMed
Summary
This summary is machine-generated.

Optimized starch-based wound dressings using response surface methodology (RSM) offer enhanced swelling and mechanical strength. These affordable films utilize polyvinyl alcohol (PVA) and starch, improving wound healing potential.

Keywords:
PVAbiodegradablemachine learningoptimizationstarchwound dressings

More Related Videos

Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
09:17

Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management

Published on: February 28, 2025

395
Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
06:45

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems

Published on: May 2, 2025

489

Related Experiment Videos

Last Updated: Jun 20, 2026

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing
04:09

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing

Published on: December 13, 2024

697
Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
09:17

Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management

Published on: February 28, 2025

395
Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
06:45

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems

Published on: May 2, 2025

489

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Wound Healing Technologies

Background:

  • Effective wound dressings require optimal swelling, degradation, and mechanical properties.
  • Starch and polyvinyl alcohol (PVA) are promising biopolymers for wound dressing applications.
  • Formulation optimization is crucial for achieving desired material characteristics.

Purpose of the Study:

  • To optimize starch-based wound dressings using response surface methodology (RSM).
  • To characterize wound dressings based on weight loss, swelling index, and mechanical strength.
  • To identify cost-effective formulations with superior performance.

Main Methods:

  • Utilized a modified casting method for film preparation.
  • Employed response surface methodology (RSM) for experimental design and analysis.
  • Characterized wound dressings by measuring weight loss (WL%), swelling index (SI%), and tensile strength (TS).

Main Results:

  • An optimized film formulation (1% PVA, 2% starch, 1.5% citric acid, 1.5% glycerol) showed excellent swelling (343.52%) and tensile strength (8.82 MPa).
  • In vitro degradation was suitable (53.22%) with optimized component ratios.
  • PVA-starch and PVA-citric acid interactions significantly influenced swelling index and other properties.

Conclusions:

  • Starch-based/PVA films optimized via RSM offer a cost-effective solution for advanced wound dressings.
  • The study identified key formulation parameters influencing wound dressing performance.
  • Optimized films demonstrate potential for improved wound healing applications.