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"Panic disorder" in schizophrenia.

L Sandberg¹, S G Siris

¹Department of Psychiatry, Mount Sinai School of Medicine, City University of New York, New York.

The Journal of Nervous and Mental Disease

|October 1, 1987

Summary

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This study details a chronic schizophrenia patient experiencing panic attacks, which worsened psychosis symptoms. Alprazolam, alongside fluphenazine decanoate, effectively reduced these panic and psychotic episodes.

Area of Science:

Psychiatry
Clinical Psychology
Neuroscience

Background:

Chronic schizophrenia is a complex mental disorder often presenting with positive, negative, and cognitive symptoms.
Panic attacks are characterized by intense fear and physical symptoms, typically diagnosed in non-schizophrenic populations.
Understanding comorbid conditions in schizophrenia is crucial for effective treatment.

Observation:

A patient diagnosed with chronic schizophrenia experienced recurrent episodes of intense apprehension and autonomic hyperactivity.
These episodes, resembling panic attacks, were associated with transient exacerbations of delusional and hallucinatory symptoms.
The patient was receiving fluphenazine decanoate for schizophrenia management.

Findings:

The co-occurrence of panic-like attacks and psychosis exacerbation in chronic schizophrenia was observed.

Related Experiment Videos

Alprazolam, administered as an adjunct to fluphenazine decanoate, demonstrated efficacy in alleviating both panic and psychotic symptoms.

This suggests a potential therapeutic benefit of benzodiazepines in managing specific symptom clusters in schizophrenia.

Implications:

The findings suggest that panic attacks may be an underrecognized phenomenon in chronic schizophrenia.
The successful adjunctive use of alprazolam highlights potential treatment avenues for comorbid panic symptoms in schizophrenia.
Further research is warranted to explore the diagnostic criteria and therapeutic strategies for panic attacks in schizophrenia patients.