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Planned Parenthood experience with triphasil.

M S Hanson1, G K Stewart, R C Bechtel

  • 1Planned Parenthood of Minnesota, Minneapolis 55404.

The Journal of Reproductive Medicine
|August 1, 1987
PubMed
Summary

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This summary is machine-generated.

Triphasil, a low-dose oral contraceptive, demonstrated high efficacy with only one pregnancy in 361 woman-years, highlighting its effectiveness when used correctly. This study confirms Triphasil

Area of Science:

  • Reproductive Health
  • Pharmacology
  • Clinical Trials

Background:

  • Oral contraceptives are widely used for pregnancy prevention.
  • Low-dose formulations aim to balance efficacy with reduced side effects.
  • Understanding the real-world performance of combined oral contraceptives is crucial.

Purpose of the Study:

  • To evaluate the efficacy and side effect profile of Triphasil, a low-dose oral contraceptive.
  • To assess the Pearl Index and method failure rate of Triphasil in a clinical setting.

Main Methods:

  • A clinical trial involving 317 women aged 18-34 years.
  • Participants used Triphasil (levonorgestrel and ethinyl estradiol) for 4,692 cycles.
  • Data collected on pregnancy rates, cycle characteristics, and adverse events.
Keywords:
BiologyContraceptionContraception TerminationContraceptive AgentsContraceptive Agents, EstrogenContraceptive Agents, FemaleContraceptive Agents, ProgestinContraceptive Methods--pharmacodynamicsContraceptive UsageData AnalysisData CollectionDelivery Of Health CareDemographic FactorsEndocrine SystemEthinyl EstradiolEvaluationExaminations And DiagnosesFamily PlanningFamily Planning CentersFertilityFertility MeasurementsHealthHealth FacilitiesHormonesLevonorgestrelMeasurementMenstrual CycleMenstruationMethod AcceptabilityOral Contraceptives, Low-dose--pharmacodynamicsOral Contraceptives--pharmacodynamicsPhysiologyPopulationPopulation DynamicsPregnancy RateReproductionReproductive BehaviorReproductive Control AgentsResearch Methodology

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Main Results:

  • An uncorrected Pearl Index of 0.28 pregnancies per 100 woman-years was observed.
  • 100% efficacy was noted when Triphasil was taken properly, with no method failures.
  • Common side effects included breakthrough bleeding (3.2%), spotting (4.4%), and mild gastrointestinal symptoms.

Conclusions:

  • Triphasil is a highly effective oral contraceptive with a low pregnancy rate.
  • The contraceptive demonstrates a favorable side effect profile in the studied population.
  • Proper adherence to Triphasil regimen is key to achieving maximum contraceptive efficacy.