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Correlation of mJOA, PROMIS physical function, and patient satisfaction in patients with cervical myelopathy: an
Mathieu Squires1, Lonni Schultz2, Jason Schwalb2
1Department of Orthopedic Surgery, University of Michigan, 1500 E Medical Center Dr, Ann Arbor, MI 48109, USA.
Background Context:
Patient-reported outcomes (PROs) are increasingly utilized to evaluate the efficacy and value of spinal procedures. Among patients with cervical myelopathy, the modified Japanese Orthopaedic Association (mJOA) remains the standard instrument, with Patient-Reported Outcomes Measurement Information System (PROMIS) physical function (PF) and patient satisfaction also frequently assessed. These outcomes have not all been directly compared using a large spine registry at 2 years follow-up for cervical myelopathic patients undergoing surgery.
Purpose:
To determine the correlation and association of PROMIS PF, mJOA, and patient satisfaction outcomes in patients undergoing surgery for cervical myelopathy.
Study Design/Setting:
Retrospective review of a multicenter spine registry database.
Patient Sample:
Adult patients with cervical myelopathy who underwent cervical spine surgery between 2/26/2018 and 4/17/2021.
Outcome Measures:
PROMIS PF, mJOA, and North American Spine Society (NASS) patient satisfaction index.
Methods:
The MSSIC database was accessed to gather pre- and postoperative outcome data on patients with cervical myelopathy. Spearman's correlation coefficients relating mJOA and PROMIS PF were quantified up to 2 years postoperatively. The correlations between patient satisfaction with mJOA and PROMIS were determined. Kappa statistics were used to evaluate for agreement between those reaching the minimum clinically important difference (MCID) for mJOA and PROMIS PF. Odds ratios were calculated to determine the association between patient satisfaction and those reaching MCID for mJOA and PROMIS PF. Support for MSSIC is provided by BCBSM and Blue Care Network as part of the BCBSM Value Partnerships program.
Results:
Data from 2,023 patients were included. Moderate to strong correlations were found between mJOA and PROMIS PF at all time points (p<.001). These outcomes had fair agreement at all postoperative time points when comparing those who reached MCID. Satisfaction was strongly related to changes from baseline for both mJOA and PROMIS PF at all time points (p<.001). Odds ratios associating satisfaction with PROMIS PF MCID were higher at all time points compared with mJOA, although the differences were not significant.
Conclusions:
PROMIS PF has a strong positive correlation with mJOA up to 2 years postoperatively in patients undergoing surgery for cervical myelopathy, with similar odds of achieving MCID with both instruments. Patient satisfaction is predicted similarly by these outcome measures by 2 years postoperatively. These results affirm the validity of PROMIS PF in the cervical myelopathic population. Given its generalizability and ease of use, PROMIS PF may be a more practical outcome measure for clinical use compared with mJOA.
Insights
Patient-reported outcomes for cervical myelopathy surgery show Patient-Reported Outcomes Measurement Information System (PROMIS) physical function (PF) strongly correlates with the modified Japanese Orthopaedic Association (mJOA) scale. Both PROMIS PF and mJOA predict patient satisfaction similarly two years post-surgery.
Area of Science:
- Spine surgery outcomes research
- Orthopedics
- Patient-reported outcome measures
Background:
- Patient-reported outcomes (PROs) are crucial for evaluating spinal procedure efficacy.
- The modified Japanese Orthopaedic Association (mJOA) scale is standard for cervical myelopathy, alongside PROMIS physical function (PF) and patient satisfaction.
- Direct comparison of these outcomes at 2 years post-surgery in a large registry was lacking.
Purpose of the Study:
- To determine the correlation and association between PROMIS PF, mJOA, and patient satisfaction in cervical myelopathy surgery patients.
- To compare the utility of PROMIS PF and mJOA in assessing surgical outcomes for cervical myelopathy.
Main Methods:
- Retrospective analysis of a multicenter spine registry (MSSIC database).
- Included 2,023 adult patients with cervical myelopathy undergoing surgery between 2018 and 2021.
- Quantified correlations between mJOA and PROMIS PF using Spearman's coefficients up to 2 years postoperatively; assessed agreement and association with patient satisfaction using Kappa statistics and odds ratios.
Main Results:
- Moderate to strong correlations (p<.001) were observed between mJOA and PROMIS PF at all time points.
- Fair agreement was found when comparing those reaching the minimum clinically important difference (MCID) for both instruments.
- Patient satisfaction was strongly related to changes in both mJOA and PROMIS PF (p<.001); PROMIS PF showed higher odds of associating with satisfaction MCID.
Conclusions:
- PROMIS PF demonstrates strong positive correlation with mJOA in cervical myelopathy surgery patients up to 2 years postoperatively.
- Both PROMIS PF and mJOA similarly predict patient satisfaction at 2 years.
- PROMIS PF is a valid and potentially more practical outcome measure for clinical use due to its generalizability and ease of use.
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