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Updated: Aug 16, 2025
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Listeria monocytogenes Infection of the Brain
Published on: October 2, 2018
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[Diagnostic predictive factors in listeria meningitis]
Daisuke Kuzume1, Yuko Morimoto1, Satoshi Tsutsumi1
1Department of Neurology, Chikamori Hospital.
Rinsho Shinkeigaku = Clinical Neurology
|December 25, 2022
Summary
A higher cerebrospinal fluid (CSF) lymphocyte ratio can help diagnose listeria meningitis. A CSF lymphocyte ratio of 30% or more accurately predicts listeria meningitis, aiding in early diagnosis.
Area of Science:
- Neurology
- Infectious Diseases
- Clinical Diagnostics
Context:
- Bacterial meningitis is a serious infection affecting the central nervous system.
- Listeria meningitis, a specific form, requires timely diagnosis for effective treatment.
- Differentiating Listeria meningitis from other bacterial meningitis forms is clinically important.
Purpose:
- To identify diagnostic factors for Listeria meningitis.
- To evaluate the predictive value of cerebrospinal fluid (CSF) parameters in differentiating Listeria meningitis.
Summary:
- This study analyzed CSF and blood data from 28 bacterial meningitis patients.
- A higher CSF lymphocyte ratio was significantly associated with Listeria meningitis (OR 1.123, P=0.039).
- A CSF lymphocyte ratio of ≥30% demonstrated 100% specificity for predicting Listeria meningitis.
Impact:
- The findings suggest CSF lymphocyte ratio is a valuable tool for distinguishing Listeria meningitis.
- This could lead to improved diagnostic strategies and patient outcomes.
- Highlights the importance of detailed CSF analysis in meningitis cases.
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