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Diabetic cardiomyopathy: Clinical phenotype and practice
Xudong Zhao1,2, Shengwang Liu3,2, Xiao Wang3,2
1Department of Endocrine and Metabolic Diseases, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Xiqing, Tianjin, China.
Frontiers in Endocrinology
|December 26, 2022
Summary
Diabetic cardiomyopathy (DCM) involves heart changes in diabetes patients, increasing heart failure risk. This review examines DCM
Area of Science:
- Cardiology
- Endocrinology
- Metabolic Diseases
Background:
- Diabetic cardiomyopathy (DCM) is a cardiac condition in diabetic individuals.
- It occurs independently of coronary artery disease and hypertension.
- DCM significantly elevates the risk of heart failure, yet effective treatments are limited.
Purpose of the Study:
- To review the literature on diabetic cardiomyopathy over the past 40 years.
- To provide an updated perspective on DCM's complex phenotype and progression.
- To explore potential clinical indicators, diagnostic criteria, and existing clinical trials for DCM.
Main Methods:
- Comprehensive literature search on diabetic cardiomyopathy.
- Analysis of studies published over the last four decades.
- Synthesis of findings regarding DCM's characteristics, progression, and management.
Main Results:
- The complex phenotype of DCM remains incompletely understood despite extensive research.
- Understanding DCM is crucial for advancing clinical and basic research.
- A comprehensive overview of DCM's progression, indicators, and trials is presented.
Conclusions:
- Diabetic cardiomyopathy presents a significant clinical challenge with poor prognosis.
- Further research is needed to fully elucidate DCM's mechanisms and improve patient outcomes.
- This review aims to consolidate current knowledge and guide future investigations into DCM.
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