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Spin echo imaging of multiple chemical shifts
J A Lohman1, R J Ordidge, A Connelly
1Oxford Research Systems Ltd., Nuffield Way, Abingdon, United Kingdom.
Magnetic Resonance in Medicine
|July 1, 1987
Summary
This study introduces a novel nuclear magnetic resonance (NMR) imaging method to separate images of different chemical species. The technique enhances image clarity by eliminating chemical-shift artifacts without increasing scan time.
Area of Science:
- Medical Imaging
- Spectroscopy
- Biophysics
Background:
- Chemical shift in Nuclear Magnetic Resonance (NMR) imaging can cause artifacts.
- Distinguishing between chemically different species in vivo is challenging.
Purpose of the Study:
- To present a method for obtaining separate cross-sectional NMR images of chemically distinct species.
- To achieve chemical-shift separation without compromising image sensitivity or experiment time.
Main Methods:
- Utilized differences in chemical shift to selectively image different chemical species.
- Employed a spin-echo 2DFT imaging technique.
- Simple addition of selectively acquired images to remove artifacts.
Main Results:
- Successfully obtained separate cross-sectional NMR images based on chemical shift differences.
- The method's total experiment time is comparable to conventional imaging.
- Demonstrated artifact-free images through image addition.
- Presented results from an in vivo human subject experiment.
Conclusions:
- The presented method effectively separates images of chemically different species using NMR.
- The technique maintains high sensitivity and efficiency, suitable for clinical applications.
- This approach offers a valuable tool for in vivo chemical imaging and artifact reduction.