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Updated: Aug 16, 2025

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A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
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Fulminant Amebic Enteritis in the Perinatal Period
Daisuke Azuma1,2, Reiko Kunisaki1,2, Tatsu Yukawa1,2
1Inflammatory Bowel Disease Center, Yokohama City University Medical Center, Japan.
Internal Medicine (Tokyo, Japan)
|December 27, 2022
Summary
Fulminant amebic enteritis in pregnancy is rare but serious. Early diagnosis and treatment are crucial, even in non-endemic areas, for better outcomes in pregnant women.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Obstetrics
Background:
- Pregnancy increases the risk of amebic enteritis.
- Fulminant amebic enteritis can be fatal.
- Diagnosis can be challenging, especially in non-endemic regions.
Observation:
- A case of a 27-year-old non-immunosuppressed pregnant woman.
- Presented with fulminant amebic enteritis complicated by cytomegalovirus enteritis.
- Required intensive care, intravenous medications, and subtotal colectomy for intestinal stenosis.
Findings:
- Amebic enteritis requires consideration in pregnant women with refractory bloody diarrhea.
- Co-infection with cytomegalovirus can complicate the presentation.
- Prompt medical and surgical intervention may be necessary.
Implications:
- Highlights the importance of considering amebic enteritis in pregnant patients with severe gastrointestinal symptoms.
- Emphasizes the need for early diagnosis and management in the perinatal period.
- Suggests that even non-immunosuppressed pregnant women are at risk for severe amebic infections.

