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Updated: Aug 15, 2025

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Published on: April 28, 2023
Unusually seen pattern of 99mTc-DPD soft tissue uptake in a patient with AL amyloidosis. Is it an amyloid type
Argyrios Doumas1, Iakovos Armenis2, Vasileios Chatzoglou3
12nd Nuclear Medicine Department, Aristotle University of Thessaloniki, Greece. adoumas@auth.gr.
Abstract:
Technetium-99m (99mTc)-labeled pyrophosphate (PYP) and 3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) are currently the most established imaging agents for the diagnosis of cardiac amyloidosis, being able to distinguish light chain (AL) from transthyretin (TTR) type of the disease. We present a pattern of increased uptake in all soft tissues, sparing the organs that are usually most affected.
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