Related Experiment Video
Updated: Aug 15, 2025

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Published on: September 25, 2019
Acute Hepatitis C After Penile Stem Cell Injection
Sahil Zaveri1, Ariana Tagliaferri2, Bhavin Shah3
1Internal Medicine, State University of New York Downstate Health Sciences University, New York, USA.
Insights
A unique case of acute hepatitis C infection occurred after a penile stem cell injection. This is the first reported instance of hepatitis C presenting acutely following this specific procedure.
Area of Science:
- Hepatology
- Infectious Diseases
- Regenerative Medicine
Background:
- Hepatitis C is a viral infection typically transmitted through blood or bodily fluids, often leading to chronic illness.
- While Hepatitis C reactivation post-transplant is documented, acute presentations are rare, particularly in immunocompetent individuals.
Observation:
- A case of acute hepatitis C infection was identified following a penile stem cell injection procedure.
- The patient was immunocompetent, making the acute presentation unusual.
Findings:
- This case represents the first documented instance of acute hepatitis C infection linked to penile stem cell injections.
- The transmission route highlights a novel risk associated with certain stem cell therapies.
Implications:
- This finding underscores the importance of screening and infection control measures in stem cell injection procedures.
- It suggests potential risks of viral transmission through non-traditional routes in regenerative medicine.
- Further research is needed to understand the transmission dynamics and prevention strategies for Hepatitis C in this context.
Abstract:
Hepatitis C is a viral infection that is transmitted via blood or other bodily fluids and usually manifests as a chronic infection. We present a unique case of acute hepatitis C from a penile stem cell injection. Although previous cases have reported the reactivation of chronic hepatitis C after hematopoietic stem cell transplantation, it is uncommon for hepatitis C to present acutely, especially in an immunocompetent patient. To our knowledge, this is the first case of acute hepatitis C after a penile stem cell injection.

