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Machine Learning in Hypertension Detection: A Study on World Hypertension Day Data
Sara Montagna1, Martino Francesco Pengo2,3, Stefano Ferretti4
1DiSPeA-University of Urbino Carlo Bo, Piazza della Repubblica 13, Urbino, 61029, Italy. sara.montagna@uniurb.it.
Insights
Machine learning (ML) algorithms show promise for improving hypertension detection. While no single ML model perfectly outperformed others, Random Forest demonstrated better prediction accuracy than current medical screening protocols for identifying individuals at risk of high blood pressure.
Area of Science:
- Cardiology
- Medical Informatics
- Data Science
Background:
- Hypertension is a major risk factor for cardiovascular events and mortality.
- Current screening programs often fail to identify individuals at high risk.
- Improved strategies are needed for early and accurate hypertension detection.
Purpose of the Study:
- To investigate the potential of machine learning (ML) algorithms in identifying predictors of hypertension.
- To compare the performance of ML models against existing medical screening protocols.
Main Methods:
- Analysis of a large dataset (20,206 individuals) from World Hypertension Day questionnaires (2015-2019).
- Testing five different ML algorithms with various balancing techniques.
- Evaluation of ML model performance against the current standard medical protocol.
Main Results:
- No single ML algorithm configuration significantly outperformed all others.
- Random Forest model showed promising results with 0.818 sensitivity and 0.629 specificity.
- Current medical protocols had higher sensitivity (0.906) but significantly lower specificity (0.230).
Conclusions:
- Machine learning approaches can enhance the precision and cost-effectiveness of hypertension screening programs.
- Accurate data collection is crucial for effective ML model performance.
- Further research is needed to identify new features and improve ML model accuracy for hypertension prediction.
Abstract:
Many modifiable and non-modifiable risk factors have been associated with hypertension. However, current screening programs are still failing in identifying individuals at higher risk of hypertension. Given the major impact of high blood pressure on cardiovascular events and mortality, there is an urgent need to find new strategies to improve hypertension detection. We aimed to explore whether a machine learning (ML) algorithm can help identifying individuals predictors of hypertension. We analysed the data set generated by the questionnaires administered during the World Hypertension Day from 2015 to 2019. A total of 20206 individuals have been included for analysis. We tested five ML algorithms, exploiting different balancing techniques. Moreover, we computed the performance of the medical protocol currently adopted in the screening programs. Results show that a gain of sensitivity reflects in a loss of specificity, bringing to a scenario where there is not an algorithm and a configuration which properly outperforms against the others. However, Random Forest provides interesting performances (0.818 sensitivity - 0.629 specificity) compared with medical protocols (0.906 sensitivity - 0.230 specificity). Detection of hypertension at a population level still remains challenging and a machine learning approach could help in making screening programs more precise and cost effective, when based on accurate data collection. More studies are needed to identify new features to be acquired and to further improve the performances of ML models.
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