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Association of Pressure Wave Reflections With Left Ventricular Mass: a Systematic Review and Meta-Analysis
Lazaros K Yofoglu1, Fotios Karachalias1, Marios K Georgakis2
1Cardiovascular Prevention and Research Unit, Clinic/Laboratory of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Greece (L.K.Y., F.K., C.T., A.A.A., A.D.P.).
Hypertension (Dallas, Tex. : 1979)
|December 30, 2022
Summary
Higher pressure wave reflections (PWRs) are linked to increased left ventricular mass. This association holds across most indices and arterial sites, particularly in middle-aged individuals with higher heart rates.
Area of Science:
- Cardiovascular physiology
- Medical diagnostics
- Biomedical engineering
Background:
- Pressure wave reflections (PWRs) are assessed noninvasively at various arterial sites.
- Conflicting data exists regarding the association between PWRs and left ventricular mass.
- This study investigates if higher PWRs correlate with increased left ventricular mass across different indices, sites, and populations.
Conclusions:
- A clinically meaningful association exists between PWRs and left ventricular mass.
- PWR reduction strategies may be beneficial for cardiovascular health.
- Future trials should focus on middle-aged individuals with high normal heart rates.
