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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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NaClO-Mediated Cross Installation of Indoles and Azoles Benefits Anticancer Hit Discovery

Changjun Yu1, Ruiyao E1, Xiao-Wei Zhang1

  • 1School of Life Sciences, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences & Research Unit of Peptide Science, Chinese Academy of Medical Sciences, 2019RU066, Lanzhou University, 199 West Donggang Road, Lanzhou, 730000, Gansu, P. R. China.

Chemmedchem
|December 30, 2022
PubMed

Keywords:
anticancerazolescross installationindoles

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