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Updated: Aug 15, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Iridociliary measurements using the Anterion swept-source optical coherence tomography
Sagarika Patyal1, Arun Kumar Yadav2, Hansel Anthony3
1Centre for Sight, New Delhi, India.
Purpose:
Anterior segment optical coherence tomography (AS-OCT) by a swept source can visualize the ciliary body. The study was performed for analyzing the feasibility of a new swept-source OCT (Anterion) device for measuring iris ciliary sulcus, ciliary body thickness, and iris thickness.
Methods:
It is a pilot study among 30 normal young participants and hospital employees with their consent. The ciliary body, iris thickness, and ciliary sulcus were measured and compared to the results in the literature. We obtained 28 good-quality results. The main outcome measures were iris thickness (near and away from the pupillary margin), ciliary body thickness, and iridociliary sulcus measurement.
Results:
The iris thickness 2.5 mm from the pupillary margin was 0.70 ± 0.10 mm in the right eye and 0.68 ± 0.11 in the left eye. Closer to the root, the iris thickness varied from 0.55 ± 0.16 mm (right eye) and 0.57 ± 0.12 (left eye). Ciliary body thickness: Right eye 0.59 ± 0.14mm (28 good images), left eye 0.58 ± 0.13mm; ciliary sulcus (inner angle): right eye 82.65 ± 26.6°, left eye 83.66 ± 30.1°.
Conclusion:
Anterion OCT is feasible in our setting for various measurements and can provide valuable inputs to ophthalmologists for the treatment of ocular diseases.
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