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Published on: December 1, 2023
Cataract surgery outcomes in pediatric patients with systemic comorbidities
Sohini Mandal1, Prafulla K Maharana1, Ritu Nagpal1
1Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Insights
Cataract surgery in children with systemic comorbidities shows improved visual acuity and significant gains in psychomotor skills. Early surgical intervention is recommended to avoid delays and optimize outcomes for pediatric patients.
Area of Science:
- Ophthalmology
- Pediatric Surgery
- Genetics and Genetic Diseases
Background:
- Cataract surgery in pediatric patients with systemic comorbidities presents unique challenges.
- Delayed diagnosis and treatment can significantly impact visual outcomes in children.
- Understanding the spectrum of comorbidities is crucial for comprehensive care.
Purpose of the Study:
- To evaluate the outcomes of cataract surgery in pediatric patients with systemic comorbidities.
- To analyze the impact of comorbidities on visual acuity and psychomotor development post-surgery.
- To identify factors contributing to delayed surgical referral in this population.
Main Methods:
- Retrospective review of medical records for 54 eyes (30 pediatric patients) who underwent cataract surgery.
- Data collected included systemic comorbidities, TORCH profile, visual acuity (BSCVA, CDVA), strabismus, nystagmus, and cataract morphology.
- Analysis of referral delays and postoperative outcomes at a tertiary-care center.
Main Results:
- The mean age of patients was 55 months; significant delays in presentation (mean 2.23 years) were noted due to referral issues.
- Common comorbidities included periventricular leukomalacia, Down's syndrome, and seizure disorders.
- Mean BSCVA improved from 1.4 logMAR preoperatively to 1.0 logMAR at 2-year follow-up; 70% of parents reported improved psychomotor skills.
Conclusions:
- Cataract surgery is beneficial for pediatric patients with systemic comorbidities, leading to improved psychomotor skills despite suboptimal visual acuity.
- Early surgical intervention and referral to specialized centers are essential to minimize delays.
- Infrastructure availability should guide surgical decisions in intellectually impaired pediatric patients with cataracts.
Purpose:
The aim of the study was to evaluate the outcomes of cataract surgery in patients of the pediatric age group with systemic comorbidities.
Methods:
Medical records of 54 eyes (30 patients) of the pediatric age group with systemic comorbidities who had undergone cataract surgery in a tertiary-care center were reviewed. The following parameters were recorded: systemic comorbidity; toxoplasmosis, rubella, cytomegalovirus, herpes simplex, HIV (TORCH) profile, best spectacle-corrected visual acuity (BSCVA), strabismus, nystagmus, and cataract morphology.
Results:
Thirty patients with a mean age of 55 months (9 months-14 years) were included. On average, every child was seen by three physicians, and the mean duration between the first visit to a physician and presentation to our center was 2.23 ± 0.67 years. The various causes for delay in referral include multiple referrals due to a lack of general anesthesia services in 78% of cases, a long waiting list at the referral hospital in 35% of cases, and a lack of awareness at the primary-care physician level in 50% of cases. The mean BSCVA at presentation was 1.4 logMAR (0.3 to 3 logMAR). The most common cataract morphology was that of zonular cataract (31.48%; 17/54). Strabismus and abnormal eye movements were observed in 27.7% (15/54) and 33.3% (18/54) of eyes, respectively. Various systemic associations were periventricular leukomalacia (12/30), Down's syndrome (6/30), seizure disorder (6/30), cardiac valvular anomalies (6/30), Marfan's syndrome (4/30), hypothyroidism (4/30), rubella (3/20), cytomegalovirus (3/20), cerebral palsy (2/30), nephrotic syndrome (2/30), Type 1 diabetes mellitus (1/30), microcephaly (1/30), cryptogenic West syndrome (1/30), congenital rubella syndrome (1/30), and Tourette syndrome (1/30). The mean postoperative corrected distance visual acuity (CDVA) at 2-year follow-up improved to 1.0 logMAR (0 to 3 logMAR). No postoperative complications were reported at the final follow-up. Around 70% of the parents reported improvement in their child's psychomotor skills.
Conclusion:
Intellectually impaired pediatric patients with cataract should be operated upon whenever there is a presence of infrastructure, and unnecessary delay in surgery should be avoided by referring the patient to higher centers. Even though objective improvement in visual acuity was suboptimal, there was definitely an improvement in the psychomotor skills of the patients.
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