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Optic neuropathy associated with acute pancreatitis: A case report
Hana Chylova1, Zora Dubska2, Martin Kyncl1
1Department of Natural Sciences, Faculty of Biomedical Engineering, Czech Technical University in Prague, 27201 Kladno, Czech Republic.
Experimental and Therapeutic Medicine
|January 2, 2023
Summary
Acute pancreatitis can cause vision loss due to visual pathway lesions. Visual evoked potentials (VEP) and MRI confirmed these changes in a young patient.
Area of Science:
- Ophthalmology
- Neurology
- Gastroenterology
Background:
- Acute pancreatitis is a serious condition with known systemic complications.
- Ocular and neurological manifestations are less common but significant.
- This case explores the link between pancreatitis and visual pathway dysfunction.
Observation:
- A 24-year-old patient presented with acute pancreatitis and simultaneous vision loss.
- Initial ophthalmological examinations (fundoscopy, OCT, fluorescein angiography, electroretinography) were normal.
- Visual evoked potentials (VEP) revealed abnormal amplitudes, and visual fields were constricted.
Findings:
- Follow-up showed progressive visual field constriction and prolonged P100 latency in VEP.
- Retinal nerve fiber layer remained stable, but optic nerve head vessel density decreased.
- Brain MRI identified non-specific white matter lesions, suggesting a central visual pathway issue.
Implications:
- This case highlights the importance of considering visual pathway lesions in pancreatitis patients with visual disturbances.
- VEP and MRI are crucial tools for diagnosing and monitoring these neurological complications.
- Early detection and management may prevent irreversible vision loss.
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